DMOZ官方文件的回答是：You should submit your site to the single most appropriate category that is directly relevant to your sites content. Please only submit your site one time. The ODP editors reserve the right to use their editorial discretion to determine which category or categories your site will ultimately be placed. 注意这里的category or categories，就是说一个网站是有可能被多个目录收录的，这完全取决于编辑员的主观判断。但一般只会被一个目录收录，如果同时被两个目录收录，被发现不合适，至少会从一个目录中被删除。有这样的案例。
DMOZ官方论坛里有编辑回答如下： Generally speaking, a business site is entitled for consideration in two categories: once in topical (by subject) and one in Regional (by physical location). But if there is no brick and mortar location for the site it is not eligible for a Regional listing.